Mexican Meatloaf with Salsa

Highlighted under: The Family Table Recipes

I absolutely love making this Mexican Meatloaf with Salsa for my family! The combination of traditional meatloaf ingredients with vibrant spices and zesty salsa gives it a delicious twist. Each bite is packed with flavor, and it’s become a favored recipe at our dinner table. Plus, it holds up well as leftovers, making it great for meal prep during the week. Believe me, you’ll want to have this easy-to-make dish on repeat for its comforting taste and simplicity in preparation.

Emily

Created by

Emily

Last updated on 2026-01-23T21:06:27.750Z

When I first experimented with this Mexican Meatloaf, I wanted to blend comforting home-cooked flavors with some of my favorite Mexican spices. After a few iterations, I nailed the perfect balance! The secret is to use a robust salsa that enhances the flavor without overpowering it.

One of the surprises for me while preparing this dish was how adding cornmeal instead of breadcrumbs keeps the meatloaf moist while giving it a slight sweet flavor that pairs beautifully with the salsa. It’s definitely a game changer and adds a wonderful texture!

Why You Will Love This Recipe

  • Spicy kick from the salsa adds excitement to the classic recipe
  • Juicy texture that remains tender thanks to the unique ingredients
  • Perfect for family gatherings or a cozy weeknight dinner

The Role of Ingredients

Each ingredient in this Mexican Meatloaf plays a crucial role in its overall flavor and texture. The ground beef serves as a hearty base, providing richness, while the salsa infuses moisture and a spicy zing. The use of cornmeal not only helps bind the meatloaf but also contributes a delightful texture that contrasts nicely with the meat. Additionally, fresh vegetables like bell peppers and onions bring vibrancy and subtle sweetness, enhancing the dish's complexity.

The spices are vital for achieving that authentic Mexican flavor profile. Cumin and chili powder add depth and warmth, while garlic delivers a fragrant aroma that beckons your taste buds. Opting for mild salsa allows the flavors to meld beautifully without overwhelming the other components, but feel free to switch to a medium or hot salsa if you want more heat.

Baking Tips and Techniques

When you bake the meatloaf, it’s important to monitor the cooking time closely. An internal temperature of 160°F (70°C) ensures that the beef is cooked through yet remains juicy. I recommend using a meat thermometer for accuracy; inserting it in the center will give you the best reading. If you notice the top browning too quickly, loosely covering it with aluminum foil can prevent overcooking while letting the inside finish baking nicely.

After baking, allowing the meatloaf to rest for 10 minutes is essential. This resting time lets the juices redistribute, preventing them from spilling out when you cut into it. Slice gently with a serrated knife to preserve its shape and keep the slices intact. Enjoying it while still warm enhances the flavors, but it also makes for great sandwiches the next day!

Storage and Serving Ideas

This Mexican Meatloaf is not just a one-time meal; it stores exceptionally well. You can keep leftovers in the refrigerator for up to four days. Make sure to wrap it tightly in plastic wrap or store it in an airtight container to maintain moisture. For longer storage, you can freeze it, either whole or in slices, for up to three months. Just thaw overnight in the fridge before reheating in the oven at 350°F (175°C) until warmed through.

When it comes to serving, consider pairing the meatloaf with Spanish rice or a fresh avocado salad for a complete meal. The vibrant flavors will complement each other beautifully! You can also elevate the experience by adding toppings like fresh cilantro, diced jalapeños, or a squeeze of lime to bring out the dish's freshness.

Ingredients

For the Meatloaf

  • 1 1/2 pounds ground beef
  • 1 cup salsa
  • 1/2 cup cornmeal
  • 1/4 cup chopped onion
  • 1/4 cup chopped bell pepper
  • 2 cloves garlic, minced
  • 1 teaspoon cumin
  • 1 teaspoon chili powder
  • 1 teaspoon salt
  • 1/2 teaspoon black pepper
  • 2 eggs

For Topping

  • 1/2 cup salsa
  • 1/2 cup shredded cheese (like cheddar or Monterey Jack)

Instructions

Steps

Preheat the Oven

Preheat your oven to 350°F (175°C) and lightly grease a loaf pan.

Combine Ingredients

In a large bowl, mix together the ground beef, salsa, cornmeal, onion, bell pepper, garlic, cumin, chili powder, salt, black pepper, and eggs until just combined.

Shape the Meatloaf

Transfer the meat mixture to the prepared loaf pan, shaping it evenly.

Add Salsa Topping

Spread 1/2 cup salsa on top of the meatloaf and sprinkle with cheese.

Bake the Meatloaf

Bake in the preheated oven for about 60 minutes or until the internal temperature reaches 160°F (70°C). Let it rest for 10 minutes before slicing.

Enjoy!

Pro Tips

  • For an extra layer of flavor, consider adding a dash of hot sauce to the meat mixture. You can also substitute ground turkey for a leaner option without sacrificing flavor.

Ingredient Substitutions

If you’re looking to customize this meatloaf, there are several substitutions you can make. For a leaner option, turkey or chicken can replace ground beef, but note that they may require additional moisture to avoid drying out. You could also use quick-cooking oats instead of cornmeal for a gluten-free version while maintaining the binding properties necessary for a good meatloaf.

For a dairy-free topping, skip the cheese or replace it with a dairy-free option like vegan cheese, which will melt nicely without altering the flavor significantly. Additionally, if you’re not a fan of salsa, try substituting it with finely chopped tomatoes or tomato sauce mixed with a dash of hot sauce for a unique twist.

Flavor Variations

To switch up the flavor profile of your meatloaf, consider incorporating different herbs and spices. Adding fresh cilantro or parsley can brighten the dish, while smoked paprika can add a deeper, smoky flavor. If you enjoy sour cream, a dollop mixed into the meat mixture can bring creaminess and a tangy element that complements the salsa well.

You can also transform it into a different dish by adding beans or jalapeños to the mixture, imbuing even more texture and spice. These variations allow for creativity in the kitchen, giving you the chance to tailor the meatloaf to suit your family's preferences or dietary restrictions.

Questions About Recipes

→ Can I use a different type of meat?

Yes, you can use ground turkey or chicken if you prefer a leaner option.

→ What can I serve with this meatloaf?

This meatloaf pairs beautifully with rice, mashed potatoes, or a fresh salad.

→ How do I store leftovers?

Store leftover meatloaf in an airtight container in the refrigerator for up to 3 days.

→ Can I freeze this meatloaf?

Absolutely! Wrap it tightly in plastic wrap or foil and store it in the freezer for up to 3 months.

Mexican Meatloaf with Salsa

I absolutely love making this Mexican Meatloaf with Salsa for my family! The combination of traditional meatloaf ingredients with vibrant spices and zesty salsa gives it a delicious twist. Each bite is packed with flavor, and it’s become a favored recipe at our dinner table. Plus, it holds up well as leftovers, making it great for meal prep during the week. Believe me, you’ll want to have this easy-to-make dish on repeat for its comforting taste and simplicity in preparation.

Prep Time15 minutes
Cooking Duration60 minutes
Overall Time75 minutes

Created by: Emily

Recipe Type: The Family Table Recipes

Skill Level: Beginner

Final Quantity: 6 servings

What You'll Need

For the Meatloaf

  1. 1 1/2 pounds ground beef
  2. 1 cup salsa
  3. 1/2 cup cornmeal
  4. 1/4 cup chopped onion
  5. 1/4 cup chopped bell pepper
  6. 2 cloves garlic, minced
  7. 1 teaspoon cumin
  8. 1 teaspoon chili powder
  9. 1 teaspoon salt
  10. 1/2 teaspoon black pepper
  11. 2 eggs

For Topping

  1. 1/2 cup salsa
  2. 1/2 cup shredded cheese (like cheddar or Monterey Jack)

How-To Steps

Step 01

Preheat your oven to 350°F (175°C) and lightly grease a loaf pan.

Step 02

In a large bowl, mix together the ground beef, salsa, cornmeal, onion, bell pepper, garlic, cumin, chili powder, salt, black pepper, and eggs until just combined.

Step 03

Transfer the meat mixture to the prepared loaf pan, shaping it evenly.

Step 04

Spread 1/2 cup salsa on top of the meatloaf and sprinkle with cheese.

Step 05

Bake in the preheated oven for about 60 minutes or until the internal temperature reaches 160°F (70°C). Let it rest for 10 minutes before slicing.

Extra Tips

  1. For an extra layer of flavor, consider adding a dash of hot sauce to the meat mixture. You can also substitute ground turkey for a leaner option without sacrificing flavor.

Nutritional Breakdown (Per Serving)

  • Calories: 380 kcal
  • Total Fat: 26g
  • Saturated Fat: 15g
  • Cholesterol: 195mg
  • Sodium: 85mg
  • Total Carbohydrates: 32g
  • Dietary Fiber: 3g
  • Sugars: 24g
  • Protein: 6g